I would say, since I personally learned this the hard way, is How to build a trustworthy team and create a good contract.
Other topics could be:
- How expensive is it to start your own game? take this from the mindset of a person who knows nothing about programming or art and just has an idea, take it from a programmers mindset, and take it from an artists/writers mindset
- Building a team - how many people should a team consist of? Is there a preference/difference based on the skills and type of game being produced?
- how about topics about advertising and social media - how to go about it and if its necessary? what if you have a small fan base? etc